Author

T. Gutsmann

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Flieger· 1 shared C. Lang· 1 shared M. Diwo· 1 shared M. Hiller· 1 shared S. Wamp· 1 shared W. Blankenfeldt· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. Flieger

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1 paper

Recent·Most cited

Structure-function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophosholipase A PlaA

M. Hiller, M. Diwo, S. Wamp, T. Gutsmann, C. Lang, W. Blankenfeldt, A. Flieger

This study reveals the structural basis for the regulated activation and substrate preference of PlaA, a lysophospholipase in Legionella pneumophila, showing how disulfide loop cleavage enhances catalytic activity and substrate specificity.

bioRxiv · Mar 24, 2023 · PreprintBiochemistry