Author

S. Wamp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Halbedel· 5 shared A. Flieger· 3 shared J. Rismondo· 2 shared P. Rothe· 2 shared A. Fruth· 1 shared A. Grundling· 1 shared A. Holzer· 1 shared A. Pietzka· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersMicrobiology

S. Halbedel

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Cytosolic factors controlling PASTA kinase-dependent ReoM phosphorylation

P. Rothe, S. Wamp, L. Rosemeyer, J. Rismondo, J. Doellinger, A. Grundling, S. Halbedel

This study identifies GpsB as an activator of PrkA, a PASTA kinase, and shows that ReoM phosphorylation is regulated by growth phase and phosphatase PrpC, with MurA's conformation and interaction with ReoM playing a key role.

bioRxiv · Apr 2, 2024Microbiology

High density genomic surveillance and risk profiling of clinical Listeria monocytogenes subtypes in Germany, 2018-2021

S. Halbedel, S. Wamp, R. Lachmann, A. Holzer, A. Pietzka, W. Ruppitsch, H. Wilking, A. Flieger

The paper analyzes genomic data from Listeria monocytogenes isolates in Germany to identify virulent and hypovirulent clones and their epidemiological patterns.

bioRxiv · Feb 16, 2024 · PreprintMicrobiology

Structure-function relationships underpin disulfide loop cleavage-dependent activation of Legionella pneumophila lysophosholipase A PlaA

M. Hiller, M. Diwo, S. Wamp, T. Gutsmann, C. Lang, W. Blankenfeldt, A. Flieger

This study reveals the structural basis for the regulated activation and substrate preference of PlaA, a lysophospholipase in Legionella pneumophila, showing how disulfide loop cleavage enhances catalytic activity and substrate specificity.

bioRxiv · Mar 24, 2023 · PreprintBiochemistry

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

S. Wamp, P. Rothe, G. Holland, S. Halbedel

The paper identifies murA escape mutations in L. monocytogenes that prevent proteolytic degradation of MurA, constitutively activating peptidoglycan biosynthesis and enhancing cephalosporin resistance.

bioRxiv · Sep 9, 2021Microbiology

PrkA controls peptidoglycan biosynthesis through the essential phosphorylation of ReoM

S. Wamp, Z. J. Rutter, J. Rismondo, C. E. Jennings, L. Moeller, R. J. Lewis, S. Halbedel

The paper identifies ReoM as a PASTA-eSTK substrate in Listeria monocytogenes, showing its phosphorylation is essential for controlling MurA degradation via ClpCP protease.

eLife · May 29, 2020Peer-reviewedMicrobiology

Population structure-guided profiling of antibiotic resistance patterns in clinical Listeria monocytogenes isolates from Germany identifies pbpB3 alleles associated with low levels of cephalosporin resistance

M. A. Fischer, S. Wamp, A. Fruth, F. Allerberger, A. Flieger, S. Halbedel

The paper analyzes antibiotic resistance in Listeria monocytogenes isolates from Germany, identifying pbpB3 alleles linked to reduced cephalosporin resistance.

bioRxiv · May 25, 2020Microbiology