AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A
A. K. Davies, D. N. Itzhak, J. R. Edgar, T. L. Archuleta, J. Hirst, L. P. Jackson, M. S. Robinson, G. H. H. Borner
The paper identifies AP-4's role in ATG9A trafficking via RUSC2-mediated vesicle transport, linking AP-4 deficiency to autophagy dysregulation in multiple cell types.
bioRxiv · Jun 11, 2018Cell Biology