Author

D. N. Itzhak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

F. McCarthy· 2 shared K. Kim· 2 shared L. Savy· 2 shared M. D. Leonetti· 2 shared M. Y. Hein· 2 shared S. B. Mehta· 2 shared A. Alloatti· 1 shared A. C. Michaelis· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

F. McCarthy

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Author profile →

4 papers

Recent·Most cited

Global organelle profiling reveals subcellular localization and remodeling at proteome scale

M. Y. Hein, D. Peng, V. Todorova, F. McCarthy, K. Kim, C. Liu, L. Savy, C. Januel, R. Baltazar-Nunez, S. Bax, S. Vaid, M. Vangipuram, I. E. Ivanov, J. R. Byrum, S. Pradeep, , M. D. Leonetti

The paper maps subcellular localization of human proteins and shows proteome remodeling during viral infection by combining organelle immuno-capture with mass spectrometry.

bioRxiv · Dec 18, 2023Cell Biology

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

N. H. Cho, K. C. Cheveralls, A.-D. Brunner, K. Kim, A. C. Michaelis, P. Raghavan, H. Kobayashi, L. Savy, J. Y. Li, H. Canaj, J. Y. S. Kim, E. M. Setwart, C. Gnann, F. McCarthy, J. P. Cabrera, , M. D. Leonetti

The paper maps human protein localization and interactions using genome engineering, imaging, and data science, revealing functional communities and RNA-binding protein subgroups.

bioRxiv · Mar 29, 2021Cell Biology

Small molecule enhancers of endosome-to-cytosol import augment anti-tumour immunity

P. Kozik, M. Gros, D. N. Itzhak, L. Joannas, J. G. Magalhaes, A. Alloatti, E. Del Nery, G. H. Borner, S. Amigorena

The paper identifies small molecule enhancers of endosome-to-cytosol antigen import that improve cross-presentation and anti-tumour immunity.

bioRxiv · May 5, 2020Immunology

AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A

A. K. Davies, D. N. Itzhak, J. R. Edgar, T. L. Archuleta, J. Hirst, L. P. Jackson, M. S. Robinson, G. H. H. Borner

The paper identifies AP-4's role in ATG9A trafficking via RUSC2-mediated vesicle transport, linking AP-4 deficiency to autophagy dysregulation in multiple cell types.

bioRxiv · Jun 11, 2018Cell Biology