Computational design of Matrix Metalloprotenaise-9 (MMP-9) resistant to auto-cleavage
A. Bonadio, S. Oguche, T. Lavy, O. Kleifeld, J. M. Shifman
The paper designs a stable MMP-9 variant resistant to auto-cleavage while maintaining enzyme activity, suitable for drug development and structural studies.
bioRxiv · Apr 11, 2023Biochemistry