A. Rozenberg

The roles of an extended N-terminal region and ETD motif in a pump-like cation channelrhodopsin discovered in a lake microbiome

This paper characterizes HulaCCR1, a novel BCCR from Lake Hula, showing the ETD motif and extended N/C-termini affect spectral tuning, gating, and membrane localization.

Robust Optogenetic Inhibition with Red-light-sensitive Anion-conducting Channelrhodopsins

The paper identifies and characterizes red-light-sensitive anion-conducting channelrhodopsins (ACRs) for optogenetic inhibition, showing improved temporal resolution in mouse neurons.

In-depth characterization of apoptosis N-terminome reveals a link between caspase-3 cleavage and post-translational N-terminal acetylation

The paper develops a method to study N-terminomes and identifies caspase-3 cleavage sites and their subsequent N-terminal acetylation during apoptosis.

Energy transfer in ubiquitous rhodopsin pumps with xanthophyll antennas

The paper detects energy transfer from hydroxylated carotenoids to rhodopsin proton pumps in marine and freshwater bacteria.

Infection cycle and phylogeny of the Polinton-like virus Phaeocystis globosa virus virophage-14T

The paper isolates and characterizes a virophage PgVV-14T that co-infects Phaeocystis globosa with PgV-14T, showing it integrates into the host genome and bridges the gap between Polinton-like viruses and virophages.

Proton-transporting heliorhodopsins from marine giant viruses

This paper identifies a light-gated proton channel in a viral heliorhodopsin from Emiliania huxleyi virus 202, showing its potential role in host manipulation and optogenetic applications.

Characterization of heliorhodopsins detected via functional metagenomics in freshwater Actinobacteria, Chloroflexi and Archaea

This paper discovers and characterizes ten new heliorhodopsins from freshwater microbes using functional metagenomics, revealing their light absorption properties and potential roles in membrane lipid remodeling and oxidative stress.

Lateral gene transfer of anion-conducting channelrhodopsins between green algae and giant viruses

The paper identifies a new family of anion-conducting channelrhodopsins (ACRs) transferred from green algae to marine giant viruses, which function in light-induced behavioral responses.

Signature activities of 20S proteasome include degradation of the ubiquitin-tag with the protein under hypoxia

The paper identifies the 20S proteasome's ability to degrade ubiquitin-tagged proteins under hypoxia and shows its role in improving cell survival.

Evolution of resistance in vitro reveals a novel mechanism of artemisinin activity in Toxoplasma gondii.

This study identifies novel mutations in Toxoplasma gondii that confer resistance to artemisinin, including mitochondrial genome amplification and changes in mitochondrial function.

Uncultured marine cyanophages encode for active NblA, phycobilisome proteolysis adaptor protein

The paper examines the functionality of nblA-like genes from marine cyanophages in a cyanobacterial knockout model, revealing a functional NblA and new insights into nblA gene distribution.