Cytogenetic resource enables mechanistic resolution of changing trends in human pluripotent stem cell aberrations linked to feeder-free culture
D. Stavish, C. J. Price, G. Gelezauskaite, K. A. Leonhard, S. M. Taapken, E. M. McIntire, O. Laing, B. M. James, J. J. Riley, J. Zerbib, D. Baker, A. L. Harding, L. H. Jestice, T. F. Eleveld, A. J. M. Gillis, , I. Barbaric
The paper analyzes genetic changes in human pluripotent stem cells under different culture conditions and identifies a link between feeder-free culture and increased chromosome 1q gains.
bioRxiv · Sep 21, 2023 · PreprintCell Biology