Author

T. Modi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

S. B. Ozkan· 3 shared I. C. Kazan· 1 shared J. Huihui· 1 shared K. Ghosh· 1 shared N. J. Ose· 1 shared P. J. Campitelli· 1 shared P. Sulc· 1 shared S. Hamilton· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

S. B. Ozkan

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3 papers

Recent·Most cited

Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics

N. J. Ose, P. J. Campitelli, T. Modi, I. C. Kazan, S. Kumar, S. B. Ozkan

The paper integrates evolutionary predictions with protein dynamics to analyze molecular adaptations of SARS-CoV-2 Spike protein, revealing allosteric interactions and mutation effects on ACE2 binding and antibody escape.

bioRxiv · Sep 14, 2023Biophysics

RNA-induced allosteric coupling drives viral capsid assembly in bacteriophage MS2

S. Hamilton, T. Modi, P. Sulc, S. B. Ozkan

This study shows RNA-induced allostery drives capsid assembly in bacteriophage MS2 by altering protein flexibility and dynamic coupling.

bioRxiv · Jun 5, 2023 · PreprintBiophysics

Ancient Thioredoxins Evolved to Modern Day Stability-Function Requirement by Altering Native State Ensemble

T. Modi, J. Huihui, K. Ghosh, S. B. Ozkan

The paper compares ancient and modern Thioredoxins to show how their native state ensemble properties evolved, affecting stability and function.

bioRxiv · Mar 4, 2018Biophysics