Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis
M. Sundqvist, A. Holdfeldt, S. Wright, T. Moller, E. Siaw, K. Jennbacken, H. Franzyk, M. Bouvier, C. Dahlgren, h. forsman
This study shows Barbadin enhances FPR2-mediated ROS production in neutrophils without affecting receptor endocytosis, suggesting AP2 plays a role in ROS release.
bioRxiv · Apr 30, 2020Pharmacology & Toxicology