Author

H. Franzyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Holdfeldt· 2 shared C. Dahlgren· 2 shared H. Forsman· 2 shared M. Sundqvist· 2 shared B. Casciaro· 1 shared E. Siaw· 1 shared F. Savini· 1 shared J. Fredriksson· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

A. Holdfeldt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural determinants in the Staphylococcus aureus derived phenol-soluble modulin-α2 peptide required for neutrophil formyl peptide receptor activation

M. Viklund, J. Fredriksson, A. Holdfeldt, S. Lind, H. Franzyk, C. Dahlgren, M. Sundqvist, H. Forsman

This study identifies structural features of PSM2 that determine its selectivity for FPR1 and FPR2 and its biased signaling properties.

bioRxiv · Oct 26, 2021Immunology

Inoculum effect of antimicrobial peptides

M. R. Loffredo, F. Savini, S. Bobone, B. Casciaro, H. Franzyk, M. L. Mangoni, L. Stella

This study systematically characterizes the inoculum effect for antimicrobial peptides, showing that their activity varies with initial cell density, challenging current screening methods.

bioRxiv · Aug 21, 2020Biophysics

Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis

M. Sundqvist, A. Holdfeldt, S. Wright, T. Moller, E. Siaw, K. Jennbacken, H. Franzyk, M. Bouvier, C. Dahlgren, h. forsman

This study shows Barbadin enhances FPR2-mediated ROS production in neutrophils without affecting receptor endocytosis, suggesting AP2 plays a role in ROS release.

bioRxiv · Apr 30, 2020Pharmacology & Toxicology