Author

T. Ntombela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Gorgulla· 2 shared H. Arthanari· 2 shared J. Blavier· 2 shared J. Olivet· 2 shared J.-C. Twizere· 2 shared K. Salehi-Ashtiani· 2 shared S. Ballet· 2 shared S. Maseko· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBiochemistry

C. Gorgulla

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Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivMar 15, 2023

Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction

J.-C. Twizere, S. Maseko, Y. Brammerloo…·O. Volkov

The paper identifies a small molecule that inhibits the Tax-1-hDLG1 interaction, reducing HTLV-1 cell-to-cell transmission in a T-cell model.

DOI 10.1016/j.antiviral.2023.105675

humanproteomics

BiochemistrybioRxivPreprintAug 25, 2021

Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule

S. Maseko, I. Van Molle, K. Blibek…·J.-C. Twizere

This study identifies the structural basis of Tax-1 interaction with syntenin-1 and demonstrates small-molecule inhibition of this interaction to target HTLV-1.

DOI 10.1101/2021.08.25.457680

humanproteomics