Author

J. Blavier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

J.-C. Twizere· 3 shared C. Gorgulla· 2 shared H. Arthanari· 2 shared J. Olivet· 2 shared K. Salehi-Ashtiani· 2 shared S. Ballet· 2 shared S. Maseko· 2 shared T. Ntombela· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersBiochemistry

J.-C. Twizere

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nanobodies against SARS-CoV-2 non-structural protein Nsp9 inhibit viral replication by targeting innate immunity

T. Venit, J. Blavier, S. B. Maseko, S. Shu, L. Espada, C. Breunig, H.-P. Holthoff, S. C. Desbordes, M. Lohse, G. Esposito, J.-C. Twizere, P. Percipalle

This paper designs nanobodies against SARS-CoV-2 Nsp9 to inhibit viral replication, showing effectiveness against multiple variants in HEK293-ACE2 cells.

bioRxiv · Oct 12, 2023 · PreprintCell Biology

Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction

J.-C. Twizere, S. Maseko, Y. Brammerloo, I. Van.Molle, A. Sogues Castrejon, C. Martin, C. Gorgulla, J. Olivet, J. Blavier, T. Ntombela, D. Frank, H. Arthanari, H. Remaut, K. Salehi-Ashtiani, S. Ballet, O. Volkov

The paper identifies a small molecule that inhibits the Tax-1-hDLG1 interaction, reducing HTLV-1 cell-to-cell transmission in a T-cell model.

bioRxiv · Mar 15, 2023Biochemistry

Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule

S. Maseko, I. Van Molle, K. Blibek, C. Gorgulla, J. Olivet, J. Blavier, C. Vandermeulen, S. Skupiewski, D. Saha, T. Ntombela, J. Lim, F. Lembo, A. Beauvois, M. Hamaidia, J.-P. Borg, , J.-C. Twizere

This study identifies the structural basis of Tax-1 interaction with syntenin-1 and demonstrates small-molecule inhibition of this interaction to target HTLV-1.

bioRxiv · Aug 25, 2021 · PreprintBiochemistry