Arp2/3 Complex Activity Enables Nuclear YAP for Naive Pluripotency of Human Embryonic Stem Cells
N. P. Meyer, T. Singh, M. L. Kutys, T. Nystul, D. L. Barber
This study identifies Arp2/3 complex activity as essential for nuclear YAP translocation and naive pluripotency in human embryonic stem cells through actin remodeling and Hippo signaling regulation.
bioRxiv · Jan 16, 2023Cell Biology