T. Pucadyil

Dynamics of membrane tubulation coupled with fission by a two-component module revealed on polymer cushioned bilayer islands

The paper uses polymer cushioned bilayer islands to study how BIN1 and Dyn2 interact to drive membrane tubulation and fission, revealing their coordinated roles in cellular processes.

Mechanistic analysis of a novel membrane-interacting variable loop in the pleckstrin-homology domain critical for dynamin function

This study investigates a novel variable loop in the dynamin PHD domain, showing that reduced hydrophobicity impairs membrane fission and CME, linking it to CMT neuropathy.

Metal-binding propensity in the mitochondrial dynamin-related protein 1

This study shows that Drp1 binds Ni2+ ions, which can be used to purify Drp1 but also inhibits its membrane fission activity.

Protein-protein interactions on membrane surfaces analysed using pull-downs with supported bilayers on silica beads

This study introduces a pull-down method using supported bilayers on silica beads to analyze protein-protein interactions on membrane surfaces, showing improved efficiency for clathrin-mediated endocytosis.