Cell Surface Glycan Engineering Reveals that Matriglycan Alone can Recapitulate Dystroglycan Binding and Function
M. O. Sheikh, C. J. Capicciotti, L. Liu, J. L. Praissman, D. G. Mead, M. A. Brindley, T. Willer, K. P. Campbell, K. W. Moremen, L. Wells, G.-J. Boons
This study shows matriglycan can independently bind Laminin, viral proteins, and antibodies, and block viral infection, suggesting it acts as a tunable receptor.
bioRxiv · May 10, 2021Biochemistry