MiR-221/222-enriched ADSC-exosome mitigates PM exposure-exacerbated cardiac ischemia/reperfusion injury through the modulation of the BNIP3/LC3B/PUMA pathway
T.-L. Lee, W.-C. Shen, Y.-C. Chen, T.-C. Lai, S.-R. Lin, S.-W. Lin, I.-S. Yu, Y.-H. Yeh, T.-K. Li, I.-T. Lee, C.-W. Lee, Y.-L. Chen
This study shows that PM exposure worsens cardiac ischemia/reperfusion injury, which is mitigated by ADSC-exosome containing miR-221/222 through modulation of the BNIP3/LC3B/PUMA pathway.
bioRxiv · Nov 10, 2023 · PreprintCell Biology