Author

Tabitha Emde

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dominika BorekiD· 3 shared Yirui GuoiD· 3 shared Alexei V. SavchenkoiD· 2 shared Bradley QuadeiD· 2 shared Elina M. KarimullinaiD· 2 shared Zbyszek OtwinowskiiD· 2 shared A. JoachimiakiD· 1 shared Alfa HerreraiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersMicrobiology

Dominika BorekORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cryo-EM structure of detergent-bound Vibrio cholerae MakA captures a candidate intermediate between the soluble form and mature assembly of an α-pore-forming toxin

Yirui Guo, Bradley Quade, Karolina P. Stepien, Tabitha Emde, Alfa Herrera, Raquel Bromberg, Robert P. Jedrzejczak, Youngchang Kim, A. Joachimiak, K.J.F. Satchell, Josep Rizo, Dominika Borek, Zbyszek Otwinowski

The paper reports a cryo-EM structure of detergent-bound Vibrio cholerae MakA, revealing its conformational changes and role in pore assembly.

bioRxiv · Sep 9, 2026 · PreprintMicrobiology

Structural architecture of TolQ-TolR inner membrane protein complex from opportunistic pathogen Acinetobacter baumannii

Elina M. Karimullina, Yirui Guo, Hanif Muhammad Khan, Tabitha Emde, Bradley Quade, Rosa Di Leo, Zbyszek Otwinowski, D. Peter Tieleman, Dominika Borek, Alexei V. Savchenko

The paper presents cryo-EM structures of the TolQ-TolR complex from Acinetobacter baumannii, revealing structural changes related to PMF energy transfer and cell envelope organization.

Science Advances · Apr 4, 2025Peer-reviewedMolecular Biology

Cryo-EM Structure of Salmonella typhimurium ArnC; the Key Enzyme in Lipid-A Modification Conferring Polymyxin Resistance

Dhruvin H. Patel, Elina M. Karimullina, Yirui Guo, Cameron Semper, Deepak T. Patel, Tabitha Emde, Dominika Borek, Alexei V. Savchenko

The paper reports cryo-EM structures of Salmonella typhimurium ArnC in apo and UDP-bound forms, revealing its tetrameric structure and conformational changes upon UDP binding.

Protein Science · Jan 25, 2025Peer-reviewedBiochemistry