Deepak T. Patel

This study analyzes the structural and functional interactions of SARS-CoV-2 Nsp3 with the 5' UTR of the viral genome, identifying key domains involved in binding and translocation.

The paper reports cryo-EM structures of Salmonella typhimurium ArnC in apo and UDP-bound forms, revealing its tetrameric structure and conformational changes upon UDP binding.

The paper provides a global atlas of predicted functional domains in Legionella pneumophila effectors using 3D structure prediction, identifying novel domains and demonstrating their functional impact.

This study determines the structure of LceB, a core effector from Legionella pneumophila, revealing its conformational flexibility, self-association, and potential host protein-binding surface.