Author

Timothy Hammond

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Alvin T. KhoiD· 1 shared Anna Blazier· 1 shared Ariel FeigliniD· 1 shared Bailin Zhang· 1 shared Beth StevensiD· 1 shared Biljana Djukic· 1 shared Bo Yang· 1 shared Clément ChatelainiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Alvin T. KhoORCID

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3 papers

Recent·Most cited

CD40 ligand and IFN-γ induce proinflammatory activity and microglia-mediated neurodegeneration in human stem cell models

Timothy Hammond, Gregory S. Wirak, Sean K. Ryan, Anna Blazier, Dongyu Liu, Ivan Nyarko-Danquah, Michael LaMorte, Shameer Khader, Jose Vela, Bo Yang, Hendrik Wesseling, Bailin Zhang, Frank Rapaport, Roopali Gandhi, Biljana Djukic, Dimitry Ofengeim

This study shows CD40L and IFN-γ induce inflammation and neurodegeneration in human stem cell-derived microglia, suggesting CD40L blockade as a potential MS therapy.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

Genetic analyses of inflammatory polyneuropathy and chronic inflammatory demyelinating polyradiculoneuropathy identified candidate genes.

Zhaohui Du, Samuel Lessard, Tejaswi Iyyanki, Michael J. Chao, FinnGen, Timothy Hammond, Dimitry Ofengeim, Katherine Klinger, Emanuele de Rinaldis, Khader Shameer, Clément Chatelain

This study identifies genetic risk loci and candidate genes for inflammatory polyneuropathy and CIDP through GWAS and functional analyses.

Human Genetics and Genomics Advances · Jun 8, 2024Peer-reviewedGenetic & Genomic Medicine

Sexual dimorphism of complement-dependent microglial synaptic pruning and other immune pathways in the developing brain

Daria Prilutsky, Alvin T. Kho, Ariel Feiglin, Timothy Hammond, Beth Stevens, Isaac S. Kohane

The paper identifies sex-specific differences in immune-related pathways, particularly complement-dependent microglial synaptic pruning, during brain development and suggests their role in sex differences in neurological disorder vulnerability.

bioRxiv · Dec 29, 2017 · PreprintNeuroscience