Author

Tingting Chen

University of Groningen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Neuroscience· 3 Bioinformatics· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Amalia M. DolgaiD· 2 shared Abhishek ChatterjeeiD· 1 shared Aiying Liu· 1 shared Angélica María Sabogal-GuáquetaiD· 1 shared Antonio Palazzo· 1 shared Caroline Suray· 1 shared Chunchun Duan· 1 shared Eugénie Genestant· 1 shared

Activity by Year

2016-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersNeuroscience

Amalia M. DolgaORCID

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Author profile →

6 papers

Recent·Most cited

A protein language model for domain, functional site, and variant effect prediction

Peng Wang, Mian Umair Ahsan, Tingting Chen, Kai Wang

PALM, a protein language model, predicts domain, functional site, and variant effects with high accuracy using curated sequence data and outperforms existing models in multiple benchmarks.

bioRxiv · Nov 5, 2026 · PreprintBioinformatics

Mating imperatives drive plasticity of the daily temporal niche in fruit flies.

Sagnik Ghosh, Ping Zhong, Caroline Suray, Junaid Mir, Tingting Chen, Antonio Palazzo, Vincent Rincheval, François Rouyer, Abhishek Chatterjee

The paper shows that sociosexual interactions in fruit flies can shift their daily activity patterns, enabling coexistence by altering temporal niches.

Nature Ecology & Evolution · Sep 22, 2026Peer-reviewedNeuroscience

Diesel exhaust particles disrupt mouse and human iPSC-derived microglial function and Amyloid-beta clearance in Alzheimer's disease models

Hong Yan, Yashvi Bhat, Polina Malahov, Angélica María Sabogal-Guáqueta, Teresa Mitchell, Tingting Chen, Eugénie Genestant, Marko Iveša, Roberto Nebbia, Phoeja S. Gadjdjoe, Sohvi Ohtonen, Tarja Malm, Xavier Guillonneau, Martina Schmidt, Amalia M. Dolga

This study shows diesel exhaust particles impair microglial function and amyloid-beta clearance in both mouse and human models, potentially contributing to Alzheimer's disease progression.

bioRxiv · Jul 23, 2026 · PreprintNeuroscience

Single-cell, label-free morphology profiling of iPSC-derived microglia reveals dynamic state transitions

Tingting Chen, Xiaopeng Li, Amalia M. Dolga

The paper develops a label-free method to track morphological changes in iPSC-derived microglia over time and identifies stimulus-specific morphological responses.

bioRxiv · Apr 29, 2026 · PreprintNeuroscience

A method for inducing a senescence trend in mesenchymal stem cells using D-galactose

Xiaoming Ji, Xiaoyu Zhou, Tingting Chen, Chunchun Duan, Wenjing Tian, Liyang Zhu, Yan Ma, Liyang Gao

This study establishes models to induce senescence in human umbilical cord mesenchymal stem cells (hUCMSCs) using D-galactose and analyzes their biological characteristics.

bioRxiv · Jan 19, 2025 · PreprintCell Biology

Transcriptome analysis revealed the possible contribution of chromosome introgression fragments from Sea Island cotton (Gossypium barbadense) to fiber strength in Upland cotton (Gossypium hirsutum)

Quanwei Lu, Yuzhen Shi, Xianghui Xiao, Pengtao Li, Juwu Gong, Aiying Liu, Haihong Shang, Wankui Gong, Tingting Chen, Qun Ge, Junwen Li, Wei Su, Shaoqi Li, Zhen Zhang, Youlu Yuan, Jinling Huang

The study identifies differentially expressed genes and functional genes associated with fiber strength in Upland cotton introgression lines with Sea Island cotton fragments.

bioRxiv · Sep 6, 2016 · PreprintGenomics