Author

Tong Lu

Shandong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Bingyu MaoiD· 2 shared Ming ShaoiD· 2 shared Pengcheng MaiD· 2 shared Aijun CheniD· 1 shared Boya Yang· 1 shared De‐Li ShiiD· 1 shared Hailing FangiD· 1 shared Jiangwei LiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Bingyu MaoORCID

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2 papers

Recent·Most cited

An interferon independent innate immune response to double stranded RNA in embryonic stem cells

Pengcheng Ma, Jianlin Xu, Tong Lu, Ronghua Luo, Yuwei Li, Jiangwei Lin, Yang Xinglou, Yongtang Zheng, Ming Shao, Bingyu Mao

This study identifies an IFN-independent innate immune response to dsRNA in mESCs, mediated by Dhx9, p53, and Stat1, which defends against dsRNA stresses and ZIKV infection.

bioRxiv · Mar 26, 2026 · PreprintImmunology

Prkra dimer senses double-stranded RNAs to dictate global translation efficiency

Tong Lu, Pengcheng Ma, Hailing Fang, Aijun Chen, Jianlin Xu, Xi Kuang, Mingyu Wang, Ling Su, Sen Wang, Yizhuang Zhang, Jiasheng Wang, Boya Yang, De‐Li Shi, Yong Zhou, Qianqian Gong, , Ming Shao

The paper identifies Prkra dimer as a dsRNA sensor that blocks translation initiation in pluripotent cells, restricting viral replication and conserved across species.

Molecular Cell · Apr 24, 2025Peer-reviewedMolecular Biology