Author

Twaritha Vijay

Calico Life Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cynthia J. KenyoniD· 2 shared Aayami Jain· 1 shared Adam FreundiD· 1 shared Andrea Ireland· 1 shared Angelica Garcia· 1 shared Antoine E. RouxiD· 1 shared Arthur D. Levinson· 1 shared B. Joy Quejarro· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersSystems Biology

Cynthia J. KenyonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Functional Screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair

Juan A. Pérez-Bermejo, Oghene Efagene, William M. Matern, Jeffrey K. Holden, Shaheen Kabir, Glen M. Chew, Gaia Andreoletti, Eniola Catton, Craig L. Ennis, Angelica Garcia, Trevor L. Gerstenberg, Kaisle A. Hill, Aayami Jain, Kristina Krassovsky, Cassandra D. Lalisan, , Kristen L. Seim

The paper identifies optimized protein-based enhancers of HDR in human HSPCs through functional screening, improving HDR efficiency without increasing off-target effects.

Nature Communications · Mar 23, 2024Peer-reviewedMolecular Biology

Partial reprogramming restores youthful gene expression through transient suppression of cell identity

Antoine E. Roux, Chunlian Zhang, Jonathan S. Paw, Jose Zavala‐Solorio, Evangelia Malahias, Twaritha Vijay, Ganesh A. Kolumam, Cynthia J. Kenyon, Jacob C. Kimmel

This study investigates how transient reprogramming affects somatic cell identity and aging in mice, finding that it can restore youthful gene expression but also suppress identity programs.

Cell Systems · Jun 10, 2022Peer-reviewedSystems Biology

Revisiting the Hayflick Limit: Insights from an Integrated Analysis of Changing Transcripts, Proteins, Metabolites and Chromatin

Michelle Chan, Han Yuan, Ilya Soifer, Tobias M. Maile, Rebecca Y. Wang, Andrea Ireland, Jonathon J. O’Brien, Jérôme Goudeau, Leanne Chan, Twaritha Vijay, Adam Freund, Cynthia J. Kenyon, Bryson D. Bennett, Fiona McAllister, David R. Kelley, , David G. Hendrickson

The paper analyzes replicative senescence in WI-38 cells using multi-omics data, finding early senescence markers, myofibroblast-like transitions, and YAP1/TEAD1 regulation.

eLife · Feb 4, 2022Peer-reviewedGenomics