Decreasing peptide deformylase activity is a beneficial strategy for increasing formaldehyde resistance in Methylobacterium extorquens
Chandler N. Hellenbrand, Tyler Miller, Elias I. Kemna, Eric L. Bruger, Zachary T. Hying, Jannell V. Bazurto
This study shows that reducing peptide deformylase activity in Methylobacterium extorquens increases formaldehyde resistance, with pleiotropic effects and tradeoffs in heat shock resistance.
bioRxiv · Apr 21, 2026 · PreprintPhysiology