The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses
B. Sodeik, M. C. Serrero, V. Girault, S. Weigang, T. M. Greco, A. Ramos Nascimento, F. Anderson, A. Piras, A. Hickford Martinez, J. Hertzog, A. Binz, A. Pohlmann, U. Prank, J. Rehwinkel, R. Bauerfeind, , G. Kochs
This study identifies MxB as an interferon-inducible GTPase that disassembles herpesvirus capsids, promoting genome release and enhancing innate immune responses.
bioRxiv · Jan 25, 2022Microbiology