Author

B. Sodeik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Goffinet· 2 shared F. Pott· 2 shared A. Bath· 1 shared A. Binz· 1 shared A. Ducroux· 1 shared A. Grothey· 1 shared A. Hickford Martinez· 1 shared A. Maciejczuk· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

C. Goffinet

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

G. D. Moschonas, L. Delhaye, R. Cooreman, F. Husers, A. Bath, D. De Sutter, E. Parthoens, A.-S. Desmet, A. Maciejczuk, H. Grzesik, S. Lippens, Z. Debyser, B. Sodeik, S. Eyckerman, X. Saelens

This study shows MX2 forms cytoplasmic condensates that mimic nuclear pore complexes to restrict HIV-1 and HSV-1 by trapping viral capsids and preventing nuclear entry.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses

B. Sodeik, M. C. Serrero, V. Girault, S. Weigang, T. M. Greco, A. Ramos Nascimento, F. Anderson, A. Piras, A. Hickford Martinez, J. Hertzog, A. Binz, A. Pohlmann, U. Prank, J. Rehwinkel, R. Bauerfeind, , G. Kochs

This study identifies MxB as an interferon-inducible GTPase that disassembles herpesvirus capsids, promoting genome release and enhancing innate immune responses.

bioRxiv · Jan 25, 2022Microbiology

A base-line cellular antiviral state is maintained by cGAS and its most frequent naturally occurring variant rs610913

J. Kazmierski, C. Elsner, K. Doehner, S. Xu, A. Ducroux, F. Pott, J. Jansen, C. W. Thorball, O. Zeymer, X. Zhou, R. Fedorov, J. Fellay, M. W. Loeffler, A. N. R. Weber, B. Sodeik, C. Goffinet

This study shows that the cGAS variant rs610913 maintains a baseline antiviral state, slightly altering susceptibility to viral infections without gross phenotypic differences.

bioRxiv · Aug 24, 2021 · PreprintImmunology

pUL36 de-ubiquitinase activity augments both the initiation and progression of lytic virus infection in IFN-primed cells

J. Mohnke, I. Stark, M. Fischer, A. Grothey, P. O'Hare, B. Sodeik, F. Erhard, L. Dölken, T. Hennig

This study shows that pUL36 DUB activity helps HSV-1 overcome IFN resistance and enhance lytic infection in IFN-primed cells.

bioRxiv · Jan 29, 2021 · PreprintMicrobiology

Human IFITM3 restricts Chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction

S. Franz, T. Zillinger, F. Pott, C. Schüler, S. Dapa, C. Fischer, V. Passos, S. Stenzel, F. Chen, K. Döhner, G. Hartmann, B. Sodeik, F. Pessler, G. Simmons, J. F. Drexler, C. Goffinet

This study shows IFITM3 restricts CHIKV and MAYV infection and is counteracted by these viruses, with a variant showing similar antiviral activity to wild-type.

bioRxiv · Sep 11, 2020Microbiology