Respiratory Syncytial virus NS1 protein targets the transactivator binding domain of MED25
V. Basse, J. Dong, A. Peres de Oliveira, P.-O. Vidalain, F. Tangy, M. Galloux, J.-F. Eleouët, C. Sizun, M. Bajorek
This paper identifies the interaction between RSV NS1 and MED25's ACID domain, showing NS1 competes with ATF6 to inhibit innate immune gene transcription.
bioRxiv · Nov 19, 2021 · PreprintMicrobiology