Potentiation of Long-Acting β2-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP
Y. Kim, V. Hou, R. D. Huff, J. A. Aguiar, S. Revill, N. Tiessen, C. Cao, M. S. Miller, M. D. Inman, K. Ask, A. C. Doxey, J. A. Hirota
This study shows that inhibiting PDE4 or ABCC4 enhances the anti-inflammatory effects of LABA/GCS in human airway epithelial cells exposed to viral stimuli.
bioRxiv · Nov 9, 2020Immunology