Nucleocapsid vaccine elicits spike-independent SARS-CoV-2 protective immunity
W. E. Matchett, V. Joag, J. M. Stolley, F. K. Shephard, C. F. Quarnstrom, C. K. Mickelson, S. Wijeyesinghe, A. G. Soerens, S. Becker, J. M. Thiede, E. Weyu, S. O'Flanagan, J. Walter, M. N. Vu, V. D. Menachery, , D. Masopust
This study shows that a nucleocapsid protein vaccine provides protective immunity against SARS-CoV-2, independent of spike protein targeting, in animal models.
bioRxiv · Apr 26, 2021Immunology