Exposure to BA.4/BA.5 Spike glycoprotein drives pan-Omicron neutralization in vaccine-experienced humans and mice
A. Muik, B. G. Lui, M. Bacher, A.-K. Wallisch, A. Toker, C. I. C. Couto, A. Gueler, V. Mampilli, G. J. Schmitt, J. Mottl, T. Ziegenhals, S. Fesser, J. Reinholz, F. Wernig, K.-G. Schraut, , U. Sahin
This study shows that exposure to BA.4/BA.5 spike glycoprotein enhances neutralizing antibody breadth against Omicron variants in vaccinated humans and mice.
bioRxiv · Sep 21, 2022 · PreprintImmunology