U. Sahin

FrameDiPT is a diffusion model for protein structure inpainting that recovers masked sections using sequence and structural context, achieving comparable accuracy to existing models with limited data.

The monovalent Omicron XBB.1.5-adapted BNT162b2 mRNA vaccine elicits stronger neutralizing antibody responses against XBB.1.5 and related sublineages than the bivalent Wild Type + Omicron BA.4/5 vaccine.

The paper shows that long-lasting mRNA-encoded IL2 restores immune responses in MHC class I-deficient cancers by activating neoantigen-specific CD8+ T cells.

The paper examines how Omicron sublineages evade neutralizing antibodies but retain T-cell epitopes, suggesting T-cell immunity remains effective against these variants.

This study compares the neutralizing antibody responses induced by monovalent and bivalent BA.4/5 vaccines against multiple Omicron sublineages in individuals over 55 years old, finding the bivalent vaccine elicits stronger neutralization.

This study shows that exposure to BA.4/BA.5 spike glycoprotein enhances neutralizing antibody breadth against Omicron variants in vaccinated humans and mice.

The paper shows that BA.2 breakthrough infection in vaccinated individuals enhances neutralization of BA.2.12.1 and BA.4/BA.5 compared to BA.1 breakthrough infection.

This study evaluates the neutralization of Omicron sublineages and Deltacron by BNT162b2 vaccine or BA.1 infection, finding BA.4/5 shows highest evasion.

The paper assesses the neutralization ability of BNT162b2-elicited sera against SARS-CoV-2 variants, finding that all sera neutralize variants to titers of ≥80, indicating vaccine effectiveness against emerging strains.

The paper assesses the neutralizing activity of BNT162b2 vaccine-induced sera against SARS-CoV-2 B.1.1.7 pseudoviruses and finds equivalent neutralizing titers compared to the Wuhan strain.