Somatic genome editing with the RCAS/TVA-CRISPR/Cas9 system for precision tumor modeling
B. Oldrini, A. Curiel-Garcia, C. Marques, V. Matia, O. Uluckan, R. Torres-Ruiz, S. Rodriguez-Perales, J. Huse, M. Squatrito
This paper develops a mouse model using RCAS/TVA-CRISPR/Cas9 for in vivo somatic genome editing to generate accurate cancer models.
bioRxiv · Aug 14, 2017Cancer Biology