V. Moreau

Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

This study shows that oncogenic β-catenin reduces exosome release in HCC, leading to immune escape by decreasing immune cell infiltration.

Loss of RND3/RHOE controls entosis through LAMP1 expression in hepatocellular carcinoma

The paper identifies Rnd3 loss as inducing entosis in hepatocellular carcinoma, with LAMP1 playing a key role in the process and correlating with metastatic potential.

The beta-catenin-target Fascin-1, altering hepatocyte differentiation, is a new marker of immature cells in hepatoblastomas

The paper investigates the role of beta-catenin in hepatoblastomas, identifying Fascin-1 as a marker of immature cells linked to loss of hepatocyte differentiation.

Discoidin domain receptor 2 drives melanoma drug resistance through AXL-dependent phenotype switching

This study shows DDR2 drives melanoma drug resistance via AXL-dependent phenotype switching, suggesting DDR inhibition as a potential second-line treatment.

Defective membrane repair machinery impairs survival of invasive cancer cells

The paper shows that defective membrane repair machinery in cancer cells impairs their survival during metastasis, with AnxA5 and AnxA6 playing key roles in repair.

DDR2 induces linear invadosome to promote angiogenesis in a fibrillar type I collagen context

This study identifies DDR2 as a key receptor for collagen that promotes angiogenesis by enabling linear invadosome formation in endothelial cells.