ImmunologybioRxiv
Non-autophagy role of Atg5 and NBR1 in unconventional secretion of IL-12 prevents gut dysbiosis and inflammation
E. F. Castillo, S. D. Merkley, S. M. Goodfellow…·J. G. In
This study shows that Atg5 in intestinal myeloid cells limits IL-12 secretion, preventing dysbiosis and inflammation by reducing IFN-gamma production.
DOI 10.1093/ecco-jcc/jjab144