E-cadherin is a structuring component of invadopodia in pancreatic cancer
A. Dobric, S. Germain, F. Silvy, R. Bonier, S. Audebert, L. Camoin, N. J. Dusetti, P. Soubeyran, J. Iovanna, V. Rigot, F. Andre
This study identifies E-cadherin as a critical structural component of invadopodia in pancreatic cancer cells, showing its role in invadopodia formation and structuration through interactions with Arp2/3, Cortactin, and MT1-MMP.
bioRxiv · Oct 9, 2020Cancer Biology