Author

V. Speranzini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

G. Mazzini· 2 shared G. Merlini· 2 shared G. Palladini· 2 shared M. Nuvolone· 2 shared P. Milani· 2 shared S. Ricagno· 2 shared T. Schulte· 2 shared A. Chaves-Sanjuan· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

G. Mazzini

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Author profile →

2 papers

Recent·Most cited

Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation

L. Broggini, M. Barzago, V. Speranzini, T. Schulte, F. Sonzini, M. Giono, M. Romeo, P. Milani, S. Caminito, G. Mazzini, P. Rognoni, G. Merlini, C. Pappone, L. Anastasia, M. Nuvolone, , S. Ricagno

This study identifies nanobodies that counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation, revealing insights into toxicity mechanisms.

bioRxiv · Aug 28, 2023Biophysics

Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter

T. Schulte, A. Chaves-Sanjuan, G. Mazzini, V. Speranzini, F. Lavatelli, F. Ferri, C. Palizzotto, M. Mazza, P. Milani, M. Nuvolone, A.-C. Vogt, G. Palladini, G. Merlini, M. Bolognesi, S. Ferro, , S. Ricagno

The paper presents a cryo-EM structure of AA amyloid fibrils from a cat with renal failure, revealing a distinct amyloid fold despite high sequence homology to human and mouse SAA.

bioRxiv · May 9, 2022Biophysics