Molecular rationale for hantavirus neutralization by a reservoir host-derived monoclonal antibody
I. Rissanen, R. Stass, S. A. Krumm, J. Seow, R. J. G. Hulswit, G. C. Paesen, J. Hepojoki, O. Vapalahti, A. Lundkvist, O. Reynard, V. Volchkov, K. J. Doores, J. T. Huiskonen, T. A. Bowden
This study investigates how a monoclonal antibody neutralizes hantaviruses by targeting the glycoprotein lattice, revealing structural insights into antibody binding and its impact on viral entry.
bioRxiv · Apr 17, 2020Microbiology