Comprehensive multi-site profiling of the malignant pleural mesothelioma micro-environment identifies candidate molecular determinants of histopathologic type
D. T. Severson, S. Freyaldenhoven, B. Wadowski, T. Hughes, Y. P. Hung, L. Chirieac, R. V. Jensen, W. G. Richards, A. A. Sedak, C. E. Gustafson, K. Vermilya, S. Innocenti, S. Korle, J. S. Barlow, M. B. Couger, , R. Bueno
This study uses single-cell RNA-sequencing and other omics data to analyze the molecular features of pleural mesothelioma subtypes and identify potential drivers of tumor cell states.
bioRxiv · May 24, 2024Cancer Biology