Complement factor C1q mediates chronic neuron loss and inflammation post-brain injury
Stephanie S. Holden, Fiorella Carla Grandi, Oumaima Aboubakr, Bryan T. Higashikubo, Frances S. Cho, Andrew H. Chang, Alejandro Osorio-Forero, Allison R. Morningstar, Vidhu Mathur, Logan J. Kuhn, Poojan Suri, Sethu Sankaranarayanan, Yaisa S. Andrews-Zwilling, Andrea J. Tenner, Anita Lüthi, , Jeanne T. Paz
This study shows that C1q mediates chronic neuron loss and inflammation after brain injury by targeting the corticothalamic circuit in mice.
Science · Sep 9, 2021Peer-reviewedNeuroscience