Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine melanoma by integrated comparative genomic analysis
W. P. D. Hendricks, V. Zismann, K. Sivaprakasam, C. Legendre, K. Poorman, W. Tembe, J. Kiefer, W. Liang, V. DeLuca, M. Stark, A. Ruhe, R. Froman, N. Duesbury, M. Washington, J. Aldrich, , J. Trent
This study identifies somatic PTPRJ mutations and dysregulated pathways in canine melanoma through genomic analysis, revealing similarities with human melanoma subtypes and potential therapeutic targets.
bioRxiv · Sep 30, 2017Cancer Biology