Author

C. Legendre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Marchal· 1 shared A. Ruhe· 1 shared A. Sekulic· 1 shared B. Davis· 1 shared B. Lamarthee· 1 shared B. Sawitzki· 1 shared C. Khanna· 1 shared D. Anglicheau· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Marchal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

From mice to humans: Cross-species transcriptomics analysis to uncover distinct mechanisms of Diabetic Retinopathy (DR)

S. Adda, C. Legendre, S. Rangasamy

This study compares transcriptomic data across mice, rats, and humans to identify conserved and species-specific molecular mechanisms of Diabetic Retinopathy.

bioRxiv · Oct 19, 2023 · PreprintPathology

CD28 costimulatory domain protects against tonic signaling-induced functional impairment in CAR-Tregs

B. Lamarthee, A. Marchal, S. Charbonnier, T. Blein, E. Martin, K. Vogt, M. Titeux, M. Delville, H. Vincon, E. Six, N. Pallet, D. Anglicheau, C. Legendre, J.-L. Taupin, B. Sawitzki, , J. Zuber

This study compares CD28 and 4-1BB costimulatory domains in CAR-Tregs, finding CD28 better preserves function and survival under tonic signaling.

bioRxiv · Nov 19, 2020 · PreprintImmunology

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine melanoma by integrated comparative genomic analysis

W. P. D. Hendricks, V. Zismann, K. Sivaprakasam, C. Legendre, K. Poorman, W. Tembe, J. Kiefer, W. Liang, V. DeLuca, M. Stark, A. Ruhe, R. Froman, N. Duesbury, M. Washington, J. Aldrich, , J. Trent

This study identifies somatic PTPRJ mutations and dysregulated pathways in canine melanoma through genomic analysis, revealing similarities with human melanoma subtypes and potential therapeutic targets.

bioRxiv · Sep 30, 2017Cancer Biology