Lysophosphatidic acid produced by Autotaxin acts as an allosteric modulator of its catalytic efficiency
F. Salgado-Polo, A. Fish, M.-T. Matsoukas, T. Heidebrecht, W.-J. Keune, A. Perrakis
The paper investigates how lysophosphatidic acid (LPA), produced by autotaxin (ATX), modulates its own catalytic efficiency through allosteric regulation.
bioRxiv · Jun 13, 2018Biochemistry