Author

A. Fish

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Perrakis· 3 shared T. Heidebrecht· 2 shared A. Adamopoulos· 1 shared A. Musacchio· 1 shared A. Priyanka· 1 shared B. van Beusekom· 1 shared C. Sacristan· 1 shared E. Pardon· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiochemistry

A. Perrakis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Surprising variety in the USP deubiquitinase catalytic mechanism

N. Keijzer, A. Priyanka, Y. Stijf-Bultsma, A. Fish, M. Gersch, T. K. Sixma

This paper reveals that USP deubiquitinases use different catalytic mechanisms, with some relying on a conserved aspartate instead of a canonical third residue for catalysis.

bioRxiv · Jul 24, 2023Biochemistry

Lysophosphatidic acid produced by Autotaxin acts as an allosteric modulator of its catalytic efficiency

F. Salgado-Polo, A. Fish, M.-T. Matsoukas, T. Heidebrecht, W.-J. Keune, A. Perrakis

The paper investigates how lysophosphatidic acid (LPA), produced by autotaxin (ATX), modulates its own catalytic efficiency through allosteric regulation.

bioRxiv · Jun 13, 2018Biochemistry

Characterisation and structure determination of a llama-derived nanobody targeting the J-base binding protein 1

B. van Beusekom, T. Heidebrecht, A. Adamopoulos, A. Fish, E. Pardon, J. Steyaert, R. Joosten, A. Perrakis

The paper characterizes a llama-derived nanobody targeting JBP1, showing high affinity and solving its crystal structure to 1.64 Å resolution, with insights into CDR flexibility.

bioRxiv · Jun 7, 2018Biochemistry

Dynamic Kinetochore Size Regulation Promotes Microtubule Capture And Chromosome Biorientation In Mitosis

C. Sacristan, M. Ahmad, J. Keller, J. Fermie, V. Groenewold, E. Tromer, A. Fish, R. Melero, J. M. Carazo, J. Klumperman, A. Musacchio, A. Perrakis, G. J. Kops

The paper shows that Spindly-based dynamic regulation of kinetochore size ensures proper microtubule capture and chromosome segregation by controlling corona expansion and shedding.

bioRxiv · Mar 12, 2018Cell Biology