Author

Wan Jin

Euler Technology (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Yi ZhangiD· 3 shared Yu XiaoiD· 3 shared Fangjin Chen· 2 shared Lingao JuiD· 2 shared Xinghuan WangiD· 2 shared Aihua YiniD· 1 shared Gang WangiD· 1 shared Huanhuan GuoiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Yi ZhangORCID

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3 papers

Recent·Most cited

A universal molecular mechanism driving aging

Wan Jin, Jing Zheng, Yu Xiao, Lingao Ju, Fangjin Chen, Jie Fu, Hui Jiang, Yi Zhang

This paper identifies DNA G-quadruplex accumulation as a universal mechanism driving aging across species by impairing epigenetic maintenance and promoting chromatin changes.

bioRxiv · Jan 6, 2024 · PreprintMolecular Biology

Tracking single cell evolution via clock-like chromatin accessibility

Yu Xiao, Wan Jin, Lingao Ju, Jie Fu, Gang Wang, Mengxue Yu, Fangjin Chen, Kaiyu Qian, Xinghuan Wang, Yi Zhang

This paper introduces EpiTrace, a method using scATAC data to estimate cell age and lineage by analyzing clock-like chromatin accessibility, revealing insights into development and aging.

bioRxiv · May 12, 2022 · PreprintBioinformatics

Developmentally Delayed Epigenetic Reprogramming Underlying the Pathogenesis of Preeclampsia

Wei He, Yuan Wei, Xiaoli Gong, Luyuan Chang, Wan Jin, Ke Liu, Xinghuan Wang, Yu Xiao, Wenjing Zhang, Qiong Chen, Kai Wu, Lili Liang, Jia Liu, Ya–Wen Chen, Huanhuan Guo, , Aihua Yin

This study identifies epigenetic reprogramming defects in preeclampsia placenta that cause developmental delay and can be detected in serum cfDNA for early prediction.

bioRxiv · May 8, 2020 · PreprintGenomics