Wei Huang

Synthetic lethality of p97 inhibition and PSMC2-overexpressionovercomes bortezomib resistance in multiple myeloma

This study identifies PSMC2 overexpression as a driver of bortezomib resistance in multiple myeloma and shows that combining p97 inhibition with bortezomib overcomes this resistance.

The Contribution of Common and Rare Genetic Variation to Emotional and Behavioural Symptoms in Childhood and Adolescence

This study examines the genetic contributions to emotional and behavioural symptoms in childhood and adolescence using common and rare variants from two large cohorts.

Expanding the repertoire of chemically induced covalent neoantigens

This study develops a chemical proteomics platform to investigate covalent neoantigen formation and demonstrates immune cell recruitment through antibody-dependent cellular phagocytosis.

The overall and sequence-specific degradation of soil extracellular DNA fragments: rates and influential factors

The paper measures overall and sequence-specific degradation rates of extracellular DNA fragments in soil and identifies factors influencing these rates.

Representation, Alignment, and Generation: A Comprehensive Survey of Foundation Models for Non-Invasive Brain Decoding

This paper surveys foundation models for non-invasive brain decoding, reviewing their applications and challenges in visual, language, and auditory domains.

scDrugAtlas: an integrative single-cell drug response database for dissecting tumor heterogeneity in therapeutic efficacy

scDrugAtlas integrates single-cell drug response data to study tumor heterogeneity and drug resistance across multiple cancer types and organisms.

Unraveling Integration-Segregation Imbalances in Schizophrenia Through Topological High-Order Functional Connectivity

This study examines topological high-order functional connectivity in schizophrenia, finding disrupted integration-segregation balance and potential diagnostic indicators.

Genetic encoding of targeted MRI contrast agents for in vivo tumor imaging

This paper develops genetically encoded magnetic nanoparticles for tumor imaging by incorporating pH-sensitive and targeting peptides, showing enhanced binding and MRI contrast in vitro and in vivo.