Author

Wei Yu

AstraZeneca (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:database / resource· 1 Research Focus:genome assembly· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Antony Simons· 1 shared B Choudhury· 1 shared Chang Liu· 1 shared Dali LiiD· 1 shared Dayin Huang· 1 shared Deqiang KongiD· 1 shared Derek E. Piper· 1 shared F Li· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

Antony Simons

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure and function of human NXPE1, a sialic acid O-acetyltransferase

H Zhang, F Li, M Zhang, Hiroyasu Konno, Wei Yu, X Min, Mousumi Paulchakrabarti, B Choudhury, Antony Simons, Derek E. Piper, H Hsu, Wenjun Ouyang

This study determines the cryo-EM structure of human NXPE1, identifies it as a sialic acid O-acetyltransferase, and shows its role in intestinal barrier function relevant to IBD.

bioRxiv · May 22, 2026 · PreprintImmunology

A rapid and efficient red-light-activated Cre recombinase system for genome engineering in mammalian cells and transgenic mice

Yang Zhou, Wei Yu, Jianli Yin, Deqiang Kong, Wenjun Li, Xinyi Wang, Yining Yao, Qin Miao Huang, Lei Li, Mengyao Liu, Longliang Qiao, Huiying Li, Junwei Zhao, Tao P. Zhong, Dali Li, , Haifeng Ye

This paper introduces REDMAPCre, a red-light-activated Cre recombinase system that enables rapid and efficient DNA recombination in mammalian cells and mice.

Nucleic Acids Research · Jul 23, 2025Peer-reviewedSynthetic Biology

Integrating immunophenotypes reveals causal relationship between tuberculosis and lung cancer: Mendelian randomization study

Xianwen Li, Dayin Huang, Chang Liu, Wei Yu, Lijun Bi

This study uses Mendelian randomization to show tuberculosis causally increases lung cancer risk, with an immune phenotype mediating this effect.

medRxiv · Jun 10, 2024 · PreprintGenetic & Genomic Medicine

A New Resource for Genomics and Precision Health Information and Publications on the Investigation and Control of COVID-19 and other Coronaviruses

Wei Yu, MARTA L. GWINN, Muin J. Khoury

The paper introduces a database that aggregates scientific literature, news, and public health resources on coronavirus research and control.

bioRxiv · Apr 21, 2020 · PreprintBioinformatics