Wen Li

Sensory cortical disinhibition is required for long-term fear memory in humans

This study uses HD-tACS and neural decoding to show that sensory cortical disinhibition is necessary for long-term fear memory in humans.

Is that clear? Robust electrophysiological measures of the effects of prior knowledge on degraded speech perception.

The paper investigates how prior knowledge affects degraded speech perception using EEG, finding strong neural correlates of perceptual evidence accumulation influenced by prior information.

From hotspot dependence to distributed robustness in resistance-aware lead optimization

The paper introduces ResistAgent, a framework for resistance-aware lead optimization that converts mutational liabilities into design objectives, improving robustness over average-affinity behavior.

Systematic evaluation of Cyanidioschyzon merolae across photobioreactor systems: Linking reactor design to biomass production and biochemical composition

This study evaluates Cyanidioschyzon merolae growth and biomass composition across different photobioreactor systems, finding that reactor design significantly impacts productivity and biochemical output.

Particle Biology: A Perspective on a First-Principles Theory of Life

This paper proposes Particle Biology as a theoretical framework to unify life science research by focusing on electromagnetic interactions at the atomic level.

Dissociable, species-specific impact of Aβ on static and dynamic functional connectomes

This paper examines how beta-amyloid affects static and dynamic functional connectomes in mice and humans, finding species-specific differences in network stability and dynamics.

Tripeptidyl peptidase II is essential for maintaining cerebrovascular homeostasis of female mice and represents a novel therapeutic target for vascular dementia

This study identifies TPP2 as essential for cerebrovascular homeostasis in female mice, linking its deficiency to vascular degeneration and cognitive impairment, and suggests Far1 as a therapeutic target.

Time- and Dose-dependent Effects of CIGB-300 in the lung squamous cell carcinoma proteomics.

This study examines the time- and dose-dependent effects of CIGB-300 on the proteome of squamous lung cancer cells, identifying potential biomarkers and mechanisms of action.

Efficient Dlx2-mediated astrocyte-to-neuron conversion and inhibition of neuroinflammation by NeuroD1

This study shows Dlx2 converts astrocytes to neurons in the striatum, but induces neuroinflammation in white matter, which is suppressed by NeuroD1.

Unraveling the causal genes and transcriptomic determinants of human telomere length

This study identifies causal genes and transcriptomic factors influencing human telomere length using placental tissue data and GWAS.