Wenbin Guo

Endosperm secretion remodels the maternal seed coat

The paper shows that the endosperm supplies cell-wall-loosening proteins to the maternal seed coat, enabling maternal cell elongation and seed growth through a regulated secretory program.

PromptBio: An Agentic Platform for End-to-End Computational Biomedical Research

PromptBio is an AI platform that translates research objectives into executable workflows, enabling reproducible and adaptable biomedical analyses.

Distinct extracellular matrix states uncouple collagen accumulation from pathological fibrosis in Duchenne muscular dystrophy

The paper shows that collagen abundance alone does not define fibrosis in DMD, as distinct matrix states with different biological activities and mechanosignaling exist.

PromptBio-Bench: Benchmarking LLM-based Bioinformatics Agents for End-to-End Data Analysis

PromptBio-Bench evaluates LLM-based bioinformatics agents across 244 tasks, showing comparable performance between Biomni and ToolsGenie but declining accuracy with task difficulty.

EoRNA2: Autonomous Data Discovery and Processing for Databasing of Gene Expression Data

EoRNA2 expands its barley gene expression database with more samples and improved infrastructure, featuring automated workflows and a new reference transcript dataset.

Dual-LLM Adversarial Framework for Information Extraction from Research Literature

The paper introduces a dual-LLM adversarial framework to improve information extraction from scientific texts, showing better performance than single-LLM and manual methods.

AtRTD2: A Reference Transcript Dataset for accurate quantification of alternative splicing and expression changes in Arabidopsis thaliana RNA-seq data

The paper develops AtRTD2, a comprehensive transcript dataset for Arabidopsis thaliana RNA-seq analysis, and introduces AtRTD2-QUASI to improve alternative splicing quantification.