Author

Mark Spensley

University of TorontoORCID 0000-0001-6167-4461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrew G. FraseriD· 2 shared Runxuan ZhangiD· 2 shared Samantha Del BorrelloiD· 2 shared Allan B James· 1 shared Amy A. CaudyiD· 1 shared Andrea BartaiD· 1 shared Cristiane P G Calixto· 1 shared Cristiane P. G. CalixtoiD· 1 shared

Activity by Year

2016-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

Andrew G. FraserORCID

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4 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 15, 2020

TranSuite: a software suite for accurate translation and characterization of transcripts

Juan Carlos Entizne, Wenbin Guo, Cristiane P. G. Calixto…·John W.S. Brown

TranSuite improves transcript translation accuracy by identifying correct ORFs and distinguishing between protein-coding and NMD substrates in Arabidopsis transcriptomes.

21 citations

ArabidopsisDNA methylation

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 4, 2019

Identification of the pathway of Rhodoquinone biosynthesis in C. elegans

Samantha Del Borrello, Margot Lautens, Kathleen Dolan…·Andrew G. Fraser

This study identifies the pathway for Rhodoquinone biosynthesis in C. elegans and develops an assay to screen for drugs blocking RQ-dependent metabolism.

DOI 10.1101/627737

C. elegansexperimental assay

𝕏 PostBluesky

GeneticsG3 Genes Genomes GeneticsPeer-reviewedJul 30, 2018

Acute effects of drugs on C. elegans movement reveal complex responses and plasticity

Mark Spensley, Samantha Del Borrello, Djina Pajkic, Andrew G. Fraser

The paper examines acute drug effects on C. elegans movement, revealing complex recovery phases and drug-specific responses that highlight biological network plasticity.

37 citations

C. elegansexperimental assay

𝕏 PostBluesky

GenomicsbioRxivMay 6, 2016

AtRTD2: A Reference Transcript Dataset for accurate quantification of alternative splicing and expression changes in Arabidopsis thaliana RNA-seq data

Runxuan Zhang, Cristiane P G Calixto, Yamile Marquez…·John W S Brown

The paper develops AtRTD2, a comprehensive transcript dataset for Arabidopsis thaliana RNA-seq analysis, and introduces AtRTD2-QUASI to improve alternative splicing quantification.

DOI 10.1093/nar/gkx267

Arabidopsisbulk RNA-seq

𝕏 PostBluesky