Humanized tauopathy chimeras uncover microglial and lncRNA strategies for neuroprotection
Wenhui Qu, Feng Li, Minwoo Wendy Jang, Pearly Ye, Ethan Cordes, Abulimiti Aikedan, Wen Hu, Ravi Kumar Nagiri, Man Ying Wong, Wenjie Luo, Mathew M. Blurton-Jones, Hagen Tilgner, Anna G. Orr, Shiaoching Gong, Li Gan
The paper develops a humanized neuroimmune model to study tauopathy and identifies microglial and lncRNA mechanisms that protect neurons.
bioRxiv · Jul 3, 2026 · PreprintNeuroscience