Author

Guillermo Coronas‐Samano

Columbia University Irving Medical CenterORCID 0000-0002-9114-3546Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Marta OlahiD· 2 shared Abulimiti AikedaniD· 1 shared Aidan C. DalyiD· 1 shared Andrew F. TeichiD· 1 shared Anthony KhairallahiD· 1 shared Basavaraju G. SanganahalliiD· 1 shared Claire Harbison· 1 shared David A. A BennettiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Marta OlahORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 26, 2026

cGAS inhibition delays TDP-43-driven ALS Pathogenesis

Yajing Liu, Weixi Feng, Abulimiti Aikedan…·Li Gan

This study identifies cGAS as a key mediator of TDP-43 pathology in ALS and shows that its inhibition reduces RNA splicing defects and neurodegeneration.

DOI 10.64898/2026.02.24.707791

humanmouse

𝕏 PostBluesky

NeuroscienceActa NeuropathologicaPeer-reviewedJul 29, 2025

Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord

John F. Tuddenham, Masashi Fujita, Emily Lee…·Marta Olah

The paper identifies microglia subsets in ALS brain and spinal cord, finding an undifferentiated phenotype and enrichment of interferon response microglia in aggressive cases.

14 citationstop 2%

humanscRNA-seq

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NeurosciencebioRxivPreprintApr 20, 2025

Behavioral deficits and exacerbated hemodynamics during lifespan of a mouse model of late onset Alzheimer's disease expressing humanized APOEϵ4 and Trem2*R47H

Misha izydorczak, Maggie Oumov, Mansiben V. Udhwani…·Justus Valentijn Verhagen

This study evaluates a mouse model of late-onset Alzheimer's disease, finding age-dependent behavioral deficits and hemodynamic changes in the olfactory bulb.

DOI 10.1101/2025.04.20.649712

mouseimaging

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